The diet to be adopted in the presence of high homocysteine is a diet that particularly takes care of the supply of water-soluble B vitamins.
What is Homocysteine
Homocysteine is an intermediate and unstable product of methionine (dietary amino acid); physiologically, it circulates 80% bound to plasma proteins (albumin) and 20% free in plasma in both reduced and oxidized form.
The homocysteine metabolism is regulated by some B vitamins, therefore, their significant and prolonged deficit can cause hyperhomocysteinemia: concentration greater than or equal to 12µmol / L.
The metabolic conversion of homocysteine depends on:
- Folic acid, Riboflavin (vit B2), Cobalamine (B12), Betaine and Zinc, which allow its re-methylation into methionine
- Pyridoxine (vit B6) which determines its transulfuration or degradation into cysteine