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Also called paraurethral glands, their function is mainly related to sexual activity: in the arousal phase of the woman, these structures contribute to the secretion of a clear and viscous liquid which, pouring into the vaginal vestibule, acts as a lubricant.
Given their position, Skene's glands are mainly involved in inflammation, during which they increase in volume and are painful.
When the channels from which the lubricating fluid flows (Skene's ducts) become blocked, cysts can result. The latter can remain asymptomatic for a long time but, if they become infected, they evolve into abscesses (ie, sac-like formations containing pus).
Other conditions that can affect the Skene's glands are trauma, neoplastic processes and congenital malformations of the genital tract.
The pathologies affecting the Skene's glands require the evaluation of the gynecologist, who can carry out the correct diagnostic classification, as well as indicating the most appropriate treatment for the specific case.
which covers the vestibule of the vagina (understood as the oval space between the labia minora), near the outlet of the distal urethra.
With respect to the orifice of the vaginal canal, Skene's glands are located in the upper part and are arranged symmetrically (one on each side).
Skene's glands are therefore surrounded by the epithelial tissue which also forms part of the labia minora and clitoris; at the vulva, these structures are connected via Skene's excretory ducts.
As the major vestibular glands (Bartolini's glands) and the minor glands scattered in the vestibule wall of the vagina, in a state of sexual arousal, these structures begin to secrete a viscous fluid which appears to contribute to vaginal lubrication during copulation.
Skene's glands are very small and not palpable (except in the presence of disease or infection).
For further information: Bartholin's Glands - What They Are, What They Are For and Associated Disorders