Carnosine G1F - Keforma

Information on Carnosine G1F - Keforma

CARNOSINE G1F - KEFORMA

Food supplement based on L-carnosine

FORMAT
Pack of 50grams

COMPOSITION

L-carnosine
Glucose 1 phosphate

Product features Carnosine G1F - Keforma

NUTRITIONAL INFORMATION

100 g

dose

Energy value

Kcal / Kj
Proteins
Fat
Carbohydrates
Glucose 1 phosphate
L-Carnosine

160/680
absent
absent
20 g
60 g
20 g

4/17
absent
absent
0.5 g
1.5 g
0.5 g

L-Carnosine- also known as beta-alanin L-histidine, is partly synthesized by the liver and partly introduced through foods of animal origin. It is estimated that the quantity of carnosine introduced daily, in a "diet that includes at least one course of animal origin, is between 50 mg and 250 mg, considering that 100 grams of beef provide about 124 mg of carnosine. This dipeptide is absorbed intact in the intestine, through a specific transporter, and from there distributed to the various tissues, in which it can be metabolized by enzymes known as carnosinase, or accumulated and used for its biological properties, which are carried out above all at the level of skeletal muscle and the brain.
Experimental evidence suggests a key role of this molecule in the control of the body's acid / base homeostasis and in the control of oxidative damage, so much so that it has been identified as an anti-aging agent. Today it is used in different clinical trials, for the prevention of neurodegenerative diseases such as Parkinson's and Alzheimer's, for neuropathies associated with diabetic disease, for the prevention of pathologies induced by ROS (oxygen free radicals) and to reduce cardiovascular risk. . However, there is no lack of studies, still in the experimental phase, which test the potential anti-neoplastic role.

For its biological properties, and for some experimental evidences that have highlighted a particular accumulation in the muscles of subjects subjected to intense training such as bodybuilders, it has also been proposed to use it in sports, with the main objective of supporting athletic performance. and reduce the feeling of fatigue. Both of these benefits derive from the role of the two amino acids that make up carnosine: histidine, which could assist the buffering and anti-free radical action, preserving the muscle from oxidative damage, and beta alanine, which could restore muscle glucose stocks by energetically supporting performance There are no clear studies to date that show the real mechanism of action of carnosine.
Glucose 1 phosphate: central is the role of glucose in energy metabolism, representing one of the main sources of sustenance of the organism.

The phosphorylated form in position 1, the one present in this supplement, is important in regulating the glycosidic flow towards glycogen synthesis. In fact, at a muscular and hepatic level, glucose 6 phosphate is converted into glucose 1 phosphate by phosphoglucomutase, thus preventing the advancement of glycolysis. In this way, glucose 1 phosphate, through a series of biochemical steps, is bound to UDP, forming UDP-glucose, necessary for the formation and structuring of glycogen. The glycogen will then be broken down during exercise or fasting in order to obtain the glucose molecules necessary to maintain the energy flow.

Rationale for use Carnosine G1F - Keforma

Numerous studies have highlighted a series of benefits deriving from the use of carnosine in sports. In most cases, these are benefits in ergogenic terms, with an increase in maximum strength, average strength and aerobic capacity. studies in which an increase in muscle mass was also recorded.
The molecular mechanism of action has not yet been clarified, but it is thought to be due to the buffering action on the one hand, which by preventing acidosis, supports muscle contraction, and to the glucogenic effect on the other, which definitely improves the properties. muscle energetics It is worth mentioning a study in which it was observed that the administration of carnosine for 3 days ensured an increase in 2.3 diphosphoglycerate, with a general improvement in aerobic capacity.
The presence of glucose 1 phosphate should support the restoration and accumulation of muscle glycogen, thus allowing an increase in energy capacity and support of athletic performance.

Method of use recommended by the company - Carnosine G1F - Keforma

Dissolve a measuring cup (2.5 g) of product in 200 ml of water.

Directions for use in sports Carnosine G1F - Keforma

For some time now, the use of this supplement in sports has been supplanted by beta alanine, which is cheaper and in any case effective in restoring muscle carnosine stores. However, currently quite varied dosages are used, ranging from 500mg to several grams per day.
Generally it is advisable to divide the intake into small doses, in order to avoid blood hydrolysis and renal excretion, making the product more available for accumulation. The presence of glucose 1 phosphate also suggests the assumption with simple sugars, in order to use the relative insulin peak to increase the muscle uptake of carnosine, and of the same glucose 1 phosphate, promoting glycogen synthesis.
Given the powdered form of this supplement, it may be useful to split the 500mg into two 250mg intakes diluted in fruit juice. Protocols are described in which 3 days of performance you can use higher dosages, even up to 1500mg.

How to optimize your business - Carnosine G1F - Keforma

As described for beta alanine supplements, the synergy with creatine has been shown to be particularly useful both in improving the ergogenic and anabolic properties, recording a significant increase in muscle mass in several studies. Furthermore, creatine has been shown to be useful in increasing muscle carnosine stores, albeit temporarily.
Particularly effective could also be the synergy with antioxidants such as vitamin E, glutathione, selenium and lipoic acid, in counteracting the damage induced by intense physical exercise with an improvement in the recovery phase.

Carnosine G1F side effects - Keforma

There does not appear to be any toxic effects associated with carnosine, especially when it is consumed at doses comparable to those that would be obtained with a healthy diet.
Doses higher than 500mg, used in anticancer trials, have proved equally safe.
In experimental models, even at doses of 50mg / kg, no side effects were recorded.
However, there is a lack of long-term clinical trials.

Precautions for use Carnosine G1F - Keforma

The product is contraindicated in cases of renal or hepatic pathology, cardiovascular disease and / or hypertension, during pregnancy, during lactation and under 14 years.

This article, elaborated on the critical rereading of scientific articles, university texts and common practice, is for information purposes only and therefore has no medical prescription value. It is therefore always required to consult your doctor, nutritionist or pharmacist before undertaking the use of any supplement.. Learn more about the critical analysis of Carnosine G1F - Keforma.

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