Like all zoonoses, rabies can be transmitted from animals to humans.
ShutterstockWhen the symptoms of rabies appear, the affected subject (man / animal) is destined to perish, as the damage caused by the pathogen is irreversible.
Rabies affects virtually all homeothermic ("warm-blooded") vertebrates, although it is generally animals with well-developed teeth (dogs, foxes) that are most at risk, as the disease is mainly transmitted by bite.
and the sun's rays. In addition, there are several disinfectants that can inactivate it, including quaternary ammonium salts, 7% iodophors and 1% soaps; these products can also be applied directly to wounds as a first intervention after a bite from a suspicious animal.it occurs mainly through the bite of the infected animal to the healthy one, as the pathogen is localized in the salivary glands, then it is eliminated with the saliva.
Other modes of transmission of the disease (even if rare) can be represented by contagion by aerosol (possible in closed environments and with a high concentration of the virus), or through the oral route (in this case micro-lesions in the mouth are necessary as the virus , if it reaches the stomach, it is inactivated by the acid pH).
(period between the infection and the onset of symptoms); moreover, the fox is used to making large movements.The mongoose represents the only reserve of Rabies in the Caribbean area.
In Russia and the Middle East, the reservoir is represented by the wolf, in the USA by the coyote, in Central / North and South America by bats; finally, in Africa, the reservoir of Anger is the jackal.
where c "is, for a short time, an" initial replication of the pathogen.
Subsequently, the Rabies virus migrates mechanically, through the structures that innervate the affected muscle (the extensions of the neurons that together form the nerve), to reach the spinal cord. From here, after having replicated further, it reaches the brain. This phase of the infection is called centripetal migration of the virus, because from the periphery (point of penetration), it reaches the central level (brain).
At this point the so-called centrifugal migration begins: that is the Rabies virus, which is localized in the brain, through the nerve that ends on the salivary glands, reaches them, replicating massively. At this stage, the animal, even if not shows obvious symptoms, can already eliminate the Rabies virus with saliva.
To conclude, the virus then spreads to the entire central nervous system, causing paralytic phenomena that will lead to death by asphyxiation (impediment of normal respiratory functions), consequent to respiratory paralysis.
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