More precisely, finasteride is an active ingredient with an azosteroid chemical structure. Initially, its use was limited to the treatment of benign prostatic hypertrophy and prostate tumors. However, by virtue of its mechanism of action, it has also proved useful in counteracting hair loss dependent on hormonal factors. For this reason, its use - at the appropriate dosages - is indicated for the treatment of androgenetic alopecia in men.
and two factors: androgen hormones (as the prefix "I will go") on the one hand and a certain genetic predisposition on the other. In particular, the hormone most involved in hair loss appears to be dihydrotestosterone (or DHT), a powerful androgenic derivative of testosterone obtained thanks to the action of an enzyme known as 5 -alpha-reductase type II.
Due to the action of dihydrotestosterone, the hair tends to thin and thin out more and more and this is due to the miniaturization of the hair follicles, the progressive reduction of the hair growth phase and the increase in the phase of involution and rest (for more information, read l "dedicated article by clicking here). Not surprisingly, therefore, generally high concentrations of DHT are found in the scalp of men with androgenetic alopecia.
However, it should be noted that progressive hair thinning does not depend only on the plasma concentration of these hormones, but also on the sensitivity of the hair follicles to their action.
, therefore systemically. Generally, the drug is formulated in the form of tablets that must be swallowed whole.Going into more detail, the medicines used to contract androgenetic alopecia contain finasteride at the concentration of 1 mg per tablet.
The dosage normally used is one finasteride 1 mg tablet to be taken once a day, with or without food.
Although shortly after taking the tablet it is possible to obtain a relatively rapid reduction in serum dihydrotestosterone levels, to obtain appreciable results, prolonged periods of intake are usually necessary. In this sense, it is very important to follow all the indications carefully. provided by the doctor; in this regard, moreover, we remind you that finasteride-based medicines against hair loss can be dispensed only upon presentation of a specific non-repeatable medical prescription and that, being classified as class C drugs, their cost is fully borne by the citizen.
and can help stop hair loss and promote hair growth.However, it should be noted that the effects of finasteride against hair loss are not the same in all patients: they could be very significant in some of them, less significant but still positive in others, while in still others the use of The active ingredient may prove to be ineffective, resulting in a certain individual variability in the response to treatment with finasteride.
Furthermore, we recall that finasteride is generally useful in male patients aged between 18 and 41 years and with live to moderate hair loss, but not with complete hair loss or with bi-temporal recession.
We conclude by saying that finasteride is NOT effective in the treatment of female androgenetic alopecia and that the active ingredient should NOT be used by women.
called PSA (prostate specific antigen); therefore, if such an analysis is to be performed, the physician should be informed of the treatment with finasteride.Furthermore, it is good to know that, following the use of finasteride for hair loss, mood alterations, depression, and - albeit less frequently - suicidal thoughts have been reported in some patients. Should similar symptoms occur, the doctor must be informed immediately.
Finally, we remind you once again that finasteride should NOT be used in women and that pregnant women - known or suspected - should NOT come into contact with broken or crumbled tablets of finasteride due to the risk of absorption of the active ingredient through the skin. . Should such absorption occur and the fetus is male, there is a risk that the baby will be born with abnormal sexual organs.
If in doubt, consult your doctor.
;Other possible side effects the frequency of which is not known include:
- Allergic reactions, even severe;
- Swelling, pain, swelling and changes in the breast, nipple discharge (in these cases, the doctor should be informed immediately as these could be signs of a serious condition such as breast cancer);
- Pain in the testicles
- Tachycardia;
- Increased levels of liver enzymes;
- Anxiety;
- Male infertility;
- Difficulty in erection, decreased libido and ejaculation disturbances which persist even after the treatment has been discontinued.
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