The reaction underlying Lyell's syndrome is evident with the formation of rashes with red plaques and bubbles, mucous erosions and epidermal detachments on different parts of the body, as if the skin had been exposed to a burning substance.
In most cases, Lyell's syndrome is drug-induced and appears to be associated with the use of particular types of drugs. Less often, the clinical picture may be triggered by an "infection," allergy or bone marrow transplant. .
From a clinical point of view, Lyell's syndrome constitutes an emergency situation due to the risks related to the destruction of the skin and the general consequences (dehydration, infectious complications, electrolyte imbalance, etc.). If not managed with intensive care, Lyell's syndrome is potentially fatal.
. This reaction is very widespread, as Lyell's syndrome involves the involvement of at least 30% of the body surface.
