So is the Rutina
Rutin or rutoside is a natural substance, a flavonoic glycoside present in plants belonging to different families, especially that of the Rutaceae (not surprisingly it takes its name from the Ruta - Ruta graveolens).
The most exploited sources for their rutin content are the sprouts of Sophora japonica (15-20%), the leaves of Eucalyptus macrorhyncha (about 10%) and those of Fagopyrum esculentum (buckwheat, 5-8%). Common foods rich in rutin include asparagus, citrus fruits (especially their peel) and berries such as blackberries and blueberries.
Property
Rutin and rutoside are sometimes improperly called vitamin P, to underline their great effectiveness in regulating the permeability of blood capillaries. It is no coincidence that they are also used in registered medicinal specialties to maintain the physiological permeability and trophism of the capillaries; in particular conditions, such as haemorrhoids, the ability of rutin to act as an anti-haemorrhagic and anti-edema can therefore have an important therapeutic role. In this sense, rutin shares the same properties as quercetin, a flavonoid contained in its molecule (such as aglycone) together with a sugary part (rutinose).
Employments
In addition to anti-hemorrhoidal treatment, rutin is also used to provide relief from symptoms related to poor circulation in the lower limbs (edema, itching, redness, varicose veins).
As an antioxidant, rutin is able to bind to divalent iron (Fe2 +) preventing its binding with hydrogen peroxide (H202); this reaction would generate highly reactive free radicals. For its antioxidant, antiplatelet and antithrombotic properties (it makes the blood "more fluid"), rutin is included in a large variety of supplements designed to promote cardiovascular health, for example in the presence of high cholesterol, obesity or reduced tolerance to glucose.
Its ability to act as an inhibitor of angiogenesis (development of new blood vessels starting from existing ones) makes rutin a current object of study for its possible anticancer properties.
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