About Thermo Stack Plus - ProAction
THERMO STACK PLUS- PROACTION
Food supplement in tablets with iodine, green tea, caffeine, citrus aurantium, chilli, fucus, cocoa, piperine.
FORMAT
Jar of 90 tablets and blister of 36 tablets
COMPOSITION
Bulking agent: microcrystalline cellulose; Bitter orange (titrated at 6% in synephrine, fruit, maltodextrin); Green tea (titrated at 98% in polyphenols of which 40% in EPGC); Caffeine; Naringina; Fucus Vesiculosus, Thallus (titrated to 0.1% iodine); Cocoa (titrated to 6% in theobromine); Carboxymethylcellulose
Anti-caking agents: silica dioxide, magnesium stearate.
Chilli, Black pepper (titrated 95% in piperine)
Coating agents: talc, starch, glycerol. Dyes: titanium dioxide and E110
Product features Thermo Stack Plus - ProAction
Thermo stack plus it is a product that can be cataloged in the complex and varied class of thermogenics. These supplements have the task of increasing thermogenesis, a process by which the body is able to maintain a constant body temperature. Thermogenesis is partly influenced by the diet, given the need to digest and absorb the various nutrients introduced (see TID , diet-induced thermogenesis): it is also closely associated with the metabolism of some tissues, such as adipose muscle, and of some organs, responsible for homeothermy and adaptive thermogenesis.
Thermogenesis inevitably affects the daily energy expenditure. The possibility of dissipating energy in the form of heat, without conversion into organic compounds, derives from the presence of futile metabolic cycles (particularly evident in less evolved animals) and from the mitochondrial activity. In particular, the presence of uncoupling proteins (UCP), allows the dissipation of the proton gradient, reducing the synthesis of ATP and favoring the production of heat. This mechanism is particularly intense at the level of brown adipose tissue - multilocular (little present in humans, very evident in hibernating animals), where UCP proteins are more expressed.
Of course, the induction of thermogenesis is not exclusively determined by an intrinsic activity of the brown adipose tissue, but finely regulated by the sympathetic nervous system, which responds effectively to external cold stimuli (preserving the internal organs from hypothermia) and hyperalimentation ( representing an effective weight control system).
It can therefore be easily deduced how the study of thermogenesis and the understanding of the mechanisms useful for its regulation can be profitably used in slimming strategies, and how significant alterations of these processes can be partly responsible for pathologies such as obesity.
Thermogenesis and supplements
Thermogenics enter the slimming process by trying to modulate thermogenesis, enhancing its effectiveness and trying to significantly increase the daily expenditure of energy. During low-calorie diets and important weight loss, however, there is a natural decrease in thermogenesis, which prevents and slows down the continuation of the slimming process. This drop in metabolism is linked to the reduction in diet-induced thermogenesis (given the reduced amount of food introduced), the modulation of thyroid function and normal organic and physiological adaptation. The use of thermogenic supplements, in this case, could therefore support the levels of adaptive thermogenesis, resulting in a significant increase in daily energy expenditure, and assist the low-calorie diet in weight loss.
Product composition in brief:
Thermo Stack Plus - ProAction
Naringina 50 mg: grapefruit flavonoid, to which it gives the characteristic bitter taste. Belonging to the falvonoid heterosides family, taken orally, it is hydrolyzed by the bacterial flora and absorbed in the intestine in the form of naringenin. There are numerous actions demonstrated for this substance, from the anti-atherogenic action to the muscle relaxant action, from the antiviral to the hepatoprotective one. Relating the active principle to the goal of the supplement, naringin is used for:
- Prolong the half-life of caffeine, reducing its clearance through the inhibition of enzymes involved in its metabolism;
Caffeine 150 mg: methylxanthine commonly introduced via coffee; an espresso, in fact, can contain up to 100mg. Caffeine is rapidly circulated and used by various tissues. It acts at different levels, on the stomach, favoring acid secretion, on the heart, increasing its frequency and contractile intensity, on the respiratory system, improving ventilatory capacity, on muscle tissue, improving its contraction, and on the nervous system, where it increases secretion of catecholamines with consequent activation of the sympathetic system, important for supporting thermogenesis. The maximum safe dose used in the studies is 300 mg, beyond which there is tremor, anxiety, tachycardia, insomnia and arousal. Prolonged use, on the other hand, represents an important risk factor for pathologies of the gastrointestinal, cardiovascular and nervous tract (migraine).
Dry extract of bitter orange 200mg: several evidences support that citrus aurantium can improve thermogenesis through a "sympathomimetic action induced by its amines, including synephrine and octopamine. More precisely it seems to be able to act selectively on the Beta 3 adrenergic receptors present in the level of adipose tissue, increasing mitochondrial functionality.
Synephrine 12mg: sympathomimetic amine also extracted from bitter orange; it is able to improve adrenergic receptor function, concentrating its activity in particular on Beta 3 receptors. men, considering that a better thermogenic and anorectic activity would be obtained in synergy with other compounds. Various disorders are associated with the intake of synephrine, from tremors to headaches, from tachycardia to hypertension up to arrhythmias and cardiac arrest; however, the potentially dangerous quantities are not known
Dry extract of fucus thallus 50 mg / iodine 50 mcg: thanks to the presence of free and conveyed iodine, mucopolysaccharides such as alginic acid and fucoidan, polyphenols and sterols, it helps to support thyroid function, improving the process of thermogenesis and increasing energy expenditure. Furthermore, the presence of alginates also gives this alga a protective action against the gastric mucosa, and potentially laxative properties.
Dry extract of cocoa beans 50mg: known for the presence of xanthines, in particular of theobromine and in a small part of caffeine and theophiline, it guarantees an enhancement of the functions previously listed for caffeine, significantly affecting cardiovascular, respiratory and cognitive function, and by enhancing sympathetic activity. At high doses, restlessness, anxiety, muscle tremors, nausea, vomiting and arrhythmias may occur.
50mg chili fruit powder: important for the presence of capsaicin, responsible for the immediate burning sensation and subsequent relief that follows its intake. The pain stress induced by this alkaloid causes a release of catecholamines and an enhancement of the sympathetic response. However, capsaicin is also known for its anti-inflammatory and pain-relieving properties.
Dry extract of black pepper fruit 2.5mg: its benefits in terms of weight loss are due to the presence of piperine, an alkaloid responsible for biological action. It has in fact been shown that the consumption of these substances can significantly affect the metabolism of other drugs and of compounds such as xanthines, enhancing their effect and increasing their bioavailability.
Rationale for integrating Thermo Stack Plus - ProAction into sports practice
The properties and therapeutic virtues of these plants have been known for centuries, so much so that they have been successfully used by the most ancient civilizations. Although for most of these substances there is a conspicuous literature concerning their biological properties, organic effects and biochemical characteristics, the efficacy of the association of several products in weight loss is not yet perfectly characterized. In the literature, however, various studies are described in which supplementation with thermogenics is associated with a
- increase of the daily caloric requirement up to 20% in sedentary subjects
- an increase in energy expenditure in subjects undergoing training
- an increase in thermogenesis, accompanied by a greater reduction in weight.
It also seems that, while observing a greater energy expenditure, and a reduction in weight, the product does not affect from a biochemical point of view by promoting lipid oxidation. Consequently, the name of FAT BURNER seems rather inadequate.
In most cases, the greatest increase in energy expenditure, the one that most affects the daily energy demand, is observed approximately 2 hours after taking the product.
Finally, it should be remembered that the use of this type of supplements only makes sense if associated with a low-calorie diet and scheduled physical activity.
Method of use recommended by the company - Thermo Stack Plus - ProAction
Take 1 tablet daily on a full stomach. It is recommended to take Thermo Stack Plus in the morning during breakfast and / or a couple of hours before physical activity.
Thermo Stack Plus Side Effects - ProAction
The presence of alkaloids and active ingredients capable of interfering with the hepatic enzyme chain, responsible for drug metabolism, could decisively alter the pharmacokinetic properties of certain active ingredients, enhancing or reducing their effects.
In the literature there is no specific indication about potential side effects associated with the administration of the product in question, therefore these should be traced back to the side effects of the individual components.
Precautions for use Thermo Stack Plus - ProAction
The Thermo Stack Plus - ProAction product is contraindicated in cases of kidney or liver disease, cardiovascular disease and / or hypertension, pregnancy, breastfeeding and under 12 years of age, as well as in adolescents not yet trained.
The Thermo Stack Plus - ProAction product must be used as part of an adequate low-calorie diet, following a healthy lifestyle with a good level of physical activity. If the diet is followed for prolonged periods of more than 3 weeks, it is advisable to seek medical advice. E-110 dye can adversely affect children's activity and attention.
This article, elaborated on the critical rereading of scientific articles, university texts and common practice, is for information purposes only and therefore has no medical prescription value. It is therefore always required to consult your doctor, nutritionist or pharmacist before undertaking the use of any supplement.. Learn more about the critical analysis of Thermo Stack Plus - ProAction.
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Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight.
Rosenbaum M, Hirsch J, Gallagher DA, Leibel RL.
Am J Clin Nutr. 2008 Oct; 88: 906-12.
JD, Lovallo WR. Influence of grapefruit juice on caffeine pharmacokinetics and pharmacodynamics. Pharmacotherapy 16: 1046-
Effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man. Br J Clin Pharmacol 35: 431-6.
R. K. Bhardwaj, H. Glaeser, L. Becquemont, U. Klotz, S. K. Gupta, M. F. Fromm.Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.. J. Pharmacol. Exp. Ther. 302: 645-5
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Phytotherapy manuals
Effects of ingesting a commercial thermogenic product on hemodynamic function and energy expenditure at rest in males and females.
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Acute effects of a thermogenic nutritional supplement on energy expenditure and cardiovascular function at rest, during low-intensity exercise, and recovery from exercise.
Ryan ED, Beck TW, Herda TJ, Smith AE, Walter AA, Stout JR, Cramer JT.
J Strength Cond Res. 2009 May; 23: 807-17.
The acute effects of the thermogenic supplement Meltdown on energy expenditure, fat oxidation, and hemodynamic responses in young, healthy males.
Jitomir J, Nassar E, Culbertson J, Moreillon J, Buford T, Hudson G, Cooke M, Kreider R, Willoughby DS.
J Int Soc Sports Nutr. 2008 Dec 16; 5: 23.
Body fat loss achieved by stimulation of thermogenesis by a combination of bioactive food ingredients: a placebo-controlled, double-blind 8-week intervention in obese subjects.
Belza A, Frandsen E, Kondrup J.
Int J Obes (Lond). 2007 Jan; 31: 121-30. Epub 2006 Apr 25.
Bioactive food stimulants of sympathetic activity: effect on 24-h energy expenditure and fat oxidation.
Belza A, Jessen AB.
Eur J Clin Nutr. 2005 Jun; 59: 733-41.
