Atopy

determined by contact, ingestion or inhalation of a given antigen (allergen).

Atopy is a disease known since ancient times, so much so that even Octavian Augustus was affected (according to the testimonies of Suetonius, reported in the work De Vita Caesarum).

, antibodies produced by the organism to defend it from the attack of potentially dangerous pathogens); IgE are produced following contact with antigen-proteins and, in case of excessive production, the organism can respond with asthma, atopic dermatitis and rhino-conjunctivitis.

Following the contact with an antigen considered allergen, an overproduction of IgE is recorded, consequently the initiation of a chain reaction is favored which causes the activation of T lymphocytes, the production of histamine and the creation of histamine-mediated processes. which cause atopy.

The cells used for the production of histamine are the basophils and mast cells, which bind to the IgE because on their surface they have the receptor for the activation of the process.

and their immune systems are more sensitive than those of adults.

With the manifestations that derive from atopy, the quality of life of the child is definitely influenced and compromised, also burdening the family. It must be borne in mind, in fact, that atopy manifests itself with asthma, rhinitis, more or less widespread eczema, itching diffuse, exudation and vesicles; to these disorders are added, then, other subjective psychological conditions, such as anxiety, insomnia, tendency to irritability, difficulty concentrating, etc.

The lesions are located mainly on the face, in particular on the cheeks and forehead, causing an "alteration of the harmonic image of the subject"; again, atopy occurs on the legs and arms, favoring the formation of lichenified areas (thick and keratinized).

The problem, seen from the eyes of a child, can be enormous and impassable, for this reason atopy conditions the quality of life of children. The life of families with at least one subject affected by atopy is also compromised: precisely, if the subject sick is a child, the usual family conditions must undergo some changes, because more attention must be paid to the child's activities, what he eats, and what he touches: even contact with clothes can predispose to atopy.

for topical application, which dismantle the symptom but not the disease; emollient, nourishing and moisturizing preparations are also useful.
In the most severe forms, the doctor recommends the use of immunosuppressive drugs; oral administration of antihistamines is useful to eliminate itching.
If the atopy is caused by the attack of pathogenic bacteria, antibiotics are able to eradicate the microorganism.
In some cases, phototherapy is an alternative method of resolving allergic symptoms.

Advances in science and modern research have proved to be exceptional, so much so that the quality of life of subjects suffering from atopy can be improved.

atopic and rhino-conjunctivitis.

Trigger

Alteration of the immune system of the subject: super production of IgE, activation of antibodies, T lymphocytes, production of histamine and outbreak of the atopic manifestation.