ELOCON ® is a drug based on Mometasone furoate
THERAPEUTIC GROUP: Non-associated corticosteroids, dermatological preparations
Indications ELOCON ® Mometasone
ELOCON ® is indicated in the treatment of dermatitis, neurodermatitis, psoriasis, eczema, sunburn and all other forms of inflammatory skin diseases sensitive to treatment with corticosteroids.
Mechanism of action ELOCON ® Mometasone
Mometasone, the active ingredient of ELOCON ®, is a recently introduced synthetic corticosteroid, with particular pharmacokinetic properties that allow the setting of therapeutic plans based on once daily doses.
In the face of these pharmacokinetic properties, the pharmacodynamic properties are instead the same as those of other corticosteroids, therefore characterized by the ability to induce the expression of proteins such as Lipocortin capable of inhibiting the enzyme Phospholipase A2, initiator of the molecular events that lead to the production of prostaglandins, chemical mediators with marked pro-inflammatory, platelet aggregating and edema activities.
All this takes the form of a prompt remission of the complained symptoms and a clear improvement in the quality of life of the affected patient.
Studies carried out and clinical efficacy
MOMETHASONE AND COLLAGEN SYNTHESIS
Skin Pharmacol. 1997; 10 (5-6): 261-4.
Effect of hydrocortisone, methylprednisolone aceponate and momethasonefuroate on collagen synthesis in human skin in vivo.
Haapasaari KM, Risteli J, Karvonen J, Oikarinen A.
Study that demonstrates how the use of mometasone together with that of other topical corticosteroids can optimize collagen synthesis, thus improving the clinical dermatological aspect.
MOMETASONE IN THE TREATMENT OF PSORIASIS
Adv Ther. 2013 May; 30: 503-16. doi: 10.1007 / s12325-013-0033-4. Epub 2013 May 25.
A novel formulation of mometasone furoate in psoriasis patients: a multicenter, randomized, double-blind clinical study.
Berg M, Svensson A, Faergemann J.
Work that evaluates the effectiveness of a new formulation based on topical Mometasone in the treatment of psoriasis, thus being able to provide another potential ally against this pathology.
MOMETASONE AND SEASONAL ALLERGIC RHINITIS
Allergy. 1999 Jan; 54: 64-9.
Onset of action of mometasone furoate nasal spray (NASONEX) in seasonal allergic rhinitis.
Berkowitz RB, Bernstein DI, LaForce C, Pedinoff AJ, Rooklin AR, Damaraju CR, Mesarina-Wicki B, Nolop KB.
Study that demonstrates the "efficacy of action" of a spray based on Mometasone in the treatment of seasonal allergic rhinitis, guaranteeing a clear improvement in symptoms.
Method of use and dosage
ELOCON ®
Cream, Ointment and 0.1% cutaneous solution of Mometasone furoate.
The particular pharmacokinetic characteristics of Mometasone make it possible to limit the application of the drug to only once a day, taking care to gently massage the affected area.
Methods of application, timing and dosages must in any case necessarily be defined by your doctor based on the patient's clinical conditions.
ELOCON ® Mometasone warnings
Therapy with ELOCON ®, like other topical therapies with corticosteroid drugs, requires compliance with different sanitary standards, necessary to limit the potential side effects of the therapy itself.
For this reason, the physician should inform patients about the appropriate behaviors to adopt and the potential side effects that the application of the drug could cause.
Avoid applying the medicine to eyes and mucous membranes, avoid using the medicine for particularly long periods of time, avoid applying the medicine to particularly large skin regions, wash your hands after each application and contact your doctor immediately following the procedure. appearance of side effects are only the main precautions that the patient should follow.
It is also recommended to store the drug out of the reach of children.
PREGNANCY AND BREASTFEEDING
The use of ELOCON ® during pregnancy and in the subsequent breastfeeding period is generally contraindicated.
However, always under the careful supervision of your doctor, its use could be justified in cases of unavoidable necessity, taking care however to avoid application on deeply damaged or particularly large areas.
Interactions
There are currently no known drug interactions worthy of clinical note.
Contraindications ELOCON ® Mometasone
The use of ELOCON ® is contraindicated in patients hypersensitive to the active substance or to one of its excipients, in patients with viral, bacterial and fungal infections not adequately treated.
Undesirable Effects - Side Effects
The use of ELOCON ®, especially if prolonged over time or carried out on particularly large or damaged areas, could cause the appearance of local adverse reactions such as edema, burning, irritation, hypertrichosis, skin atrophy, dry skin and dermatitis.
Fortunately, all potential systemic side effects are rarer.
Note
ELOCON ® is a drug subject to mandatory medical prescription.
The information on ELOCON ® Mometasone published on this page may be out of date or incomplete. For a correct use of this information, see the Disclaimer and useful information page.
