DELTA 80 ® is a drug based on Benzoyl Peroxide and Cetylpyridinium chloride
THERAPEUTIC GROUP: Anti-acne preparations for topical use
Indications DELTA 80 ® Benzoyl peroxide and Cetylpyridinium
DELTA 80 ® is indicated for skin disinfection.
Given the antiseptic capacity towards Corynebacterium Acnes, DELTA 80 ® can also be used in the treatment of acne.
Mechanism of action DELTA 80 ® Benzoyl peroxide and Cetylpyridinium
DELTA 80 ® is a medicine used as an antiseptic for the skin due to its active principles with strong broad-spectrum disinfectant power and therefore active against pathogenic microorganisms such as Corynebacterium acnes, involved in the pathogenesis of acne.
The antiseptic action is to be traced back to Benzoyl peroxide, capable of acting as an oxidizing agent against multiple microorganisms, altering the normal structure of vital molecules and compromising the functional and vital capacity of the bacteria and Cetylpyridinium chloride, quaternary ammonium salt, which thanks to its cationic and surfactant properties is able to alter the normal structure of the bacterial wall, compromising its protective and exchange function.
Following the topical use of the drug, neither of the two active ingredients is absorbed systemically, thus significantly reducing the risk of serious side effects, and at the same time preserving a high efficacy of action at the local level.
The aforementioned antiseptic and disinfectant action allows to limit the proliferation of comedogenic microbial strains, avoiding the inflammatory evolution of acne lesions.
Studies carried out and clinical efficacy
BENZOYL PEROXIDE AND ANTIBIOTICS: winning synergy
Skin Therapy Lett. 2010 Nov-Dec; 15: 5-7.
Benzoyl peroxide: enhancing antibiotic efficacy in acne management.
Dutil M.
This study demonstrates how the addition of benzoyl peroxide to the antibiotic treatment of acne can optimize its effectiveness by also acting on the amount of microorganisms normally resistant to common antibiotic therapy.
TREATMENT OF ACNE DURING PREGNANCY AND BREASTFEEDING
Drugs. 2013 Jun; 73: 779-87. doi: 10.1007 / s40265-013-0060-0.
Treatment of acne vulgaris during pregnancy and lactation.
Kong YL, Tey HL.
Yet another study that demonstrates how the use of skin antiseptics such as benzoyl peroxide certainly represents the most effective and safe therapeutic protocol for the treatment of acne during pregnancy and breastfeeding.
ANTISEPTICS AND ACNE
J Drugs Dermatol. 2013 Jun 1; 12: s73-4.
The role of benzoyl peroxide in the new treatment paradigm for acne.
Kircik LH.
Interesting and very recent study that re-evaluates the use of antiseptics and disinfectants such as benzoyl peroxide or cetylpyridinium chloride in the treatment of acne, observing how these can be in the long run more effective than antibiotics, given the reduced ability of microorganisms to put in effective resistance mechanisms act.
Method of use and dosage
DELTA 80 ®
4 g Benzoyl peroxide gel for skin use and 0.1 g Cetylpyridinium chloride per 100 g of gel.
It is recommended to apply the gel directly on the area to be treated twice a day, massaging it gently until the drug is completely absorbed.
Warnings DELTA 80 ® Benzoyl peroxide and Cetylpyridinium
DELTA 80 ® is a medicine indicated in the short and limited treatment of pimples and blackheads, therefore it should only be used for a short period of time.
In fact, its prolonged use could cause the appearance of sensitization reactions such as erythema, edema and inflammation of various kinds.
In order to obtain the maximum therapeutic efficacy, limiting the potential side effects of the therapy, the patient should avoid exposure to ultraviolet rays following the application of DELTA 80 ®, thoroughly cleanse the hands after using the drug in order to avoid contact of the product with eyes and mucous membranes, cleanse the skin region to be treated before applying the drug.
The active ingredients present in DELTA 80 ® could cause discoloration of hair and clothing.
Keep this medicine out of the reach of children.
PREGNANCY AND BREASTFEEDING
The use of DELTA 80 ® during pregnancy and in the subsequent period of breastfeeding should be justified by cases of real need and carefully supervised by your doctor.
Interactions
The patient receiving DELTA 80 ® should avoid the concomitant intake of other topical drugs.
Contraindications DELTA 80 ® Benzoyl peroxide and Cetylpyridinium
The use of DELTA 80 ® is contraindicated in patients hypersensitive to the active substance or to one of its excipients.
Undesirable Effects - Side Effects
The use of DELTA 80 ® could determine the appearance of local and transient adverse reactions such as burning or irritation.
Note
DELTA 80 ® is a non-prescription drug.
The information on DELTA 80 ® Benzoyl Peroxide and Cetylpyridinium published on this page may be out of date or incomplete. For a correct use of this information, see the Disclaimer and useful information page.
