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Injury to a blood vessel results in the rapid conversion of prothrombin (factor II) to thrombin (factor IIa), which in turn converts fibrinogen into an insoluble fibrin polymer; in this way an intertwining of fibers is produced which participates in the formation of the clot.
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In the event of a blood vessel injury, the conversion of prothrombin (factor II) to thrombin (factor IIa) occurs.
This triggers a chain reaction that leads to the formation of a blood clot.
The prothrombin time (PT = Prothrombin time) is a "laboratory analysis, which quantifies the time required for the formation of a clot:
- PT values higher than the reference ones indicate that the blood takes longer than normal to clot;
- Lower values indicate that the blood clots faster than normal.
For this, prothrombin time assessment is also prescribed when a person is taking anticoagulant drugs.
synthesized by the liver.Injury to a blood vessel results in the rapid conversion of prothrombin (factor II) to thrombin (factor IIa), which in turn converts fibrinogen into an insoluble fibrin polymer; in this way an intertwining of fibers is produced which participates in the formation of the clot.
) or as an aid in diagnosing haemostatic disorders and liver disease.
