Warning - Not to be confused with "Creatinine"
What is Creatine?
Creatine is an amino acid naturally present in the human body, where it is concentrated within the skeletal muscles; at this level we find in fact 95% of the approximately 120 grams contained in a medium-sized adult organism.
High Creatine
As mentioned in the introductory chapter, it is easy to understand how the blood concentrations of creatine increase in the presence of muscle damage, resulting from trauma or myopathies (see muscular dystrophy).
An increase in the levels of creatine in the urine is found in rheumatoid arthritis and in all those conditions that involve intense muscle catabolism (prolonged exercise, malnutrition, fever, hyperthyroidism).
However, the dosage of creatine in the blood and urine has a limited clinical use, as nowadays there are tests of other serum analytes (in particular creatine kinase and aldolase A) which allow to highlight dysfunctions of muscle metabolism in a way more specific, sensitive and accurate. The measurement of the CK MB isoenzyme concentration of creatine kinase is for example useful in the diagnosis of heart attack.
Still widely used, however, is the dosage of creatinine, a metabolite of creatine which significantly increases its plasma concentration in the presence of renal damage.
Select Blood Tests Blood Tests Uric acid - uricaemia ACTH: adrenocortitotropic hormone Alanine amino transferase, ALT, SGPT Albumin Alcoholism Alphafetoprotein Alphafetoprotein in pregnancy Aldolase Amylase Ammonemia, ammonia in the blood Androstenedione Antibody-endomysial antibodies Anti-gliadicides Nucleus Helicobacter pylori antibodies Embryo carcinoal antigen - CEA Prostate specific antigen PSA Antithrombin III Haptoglobin AST - GOT or aspartate aminotransferase Azotemia Bilirubin (physiology) Direct, indirect and total bilirubin CA 125: tumor antigen 125 CA 15-3: tumor antigen 19-9 as tumor marker Calcemia Ceruloplasmin Cystatin C CK-MB - Creatine kinase MB Cholesterolemia Cholinesterase (pseudcholinesterase) Plasma concentration Creatine kinase Creatinine Creatinine Creatinine clearance Chromogranin A D-dimer Hematocrit Blood culture Hemocrome Hemoglobin Glycated hemoglobin a Blood tests Blood tests, Down syndrome screening Ferritin Rheumatoid factor Fibrin and its degradation products Fibrinogen Leukocyte formula Alkaline phosphatase (ALP) Fructosamine and glycated hemoglobin GGT - Gamma-gt Gastrinemia GCT Glycemia Red blood cells Granulocytes HE4 and Cancer at "Ova" Immunoglobulins INR Insulinemia Lactate dehydrogenase LDH Leukocytes - white blood cells Lymphocytes Lipases Tissue damage markers MCH MCHC MCV Metanephrines MPO - Myeloperoxidase Myoglobin Monocytes MPV - average platelet volume Natremia Neutrophils Homocysteine Thyroid hormones OGTT Osmocyte Plasma protein A associated with pregnancy Peptide C Pepsin and pepsinogen PCT - platelet or platelet hematocrit PDW - distribution width of platelet volumes Platelets Plateletpenia PLT - number of platelets in blood Preparation for blood tests Prist Test Total IgEk Protein C (PC) - Protein C Activated (PCA) C Reactive Protein Rast Protein Test Specific IgE Reticulocytes Renin Reuma-Test Oxygen Saturation Sideremia BAC, BAC TBG - Thyroxine Binding Globulin Prothrombin Time Partial Thromblopastin Time (PTT) Activated Partial Thromboplastin Time (aPTT) Testosterone Testosterone: free and bioavailable fraction Thyroglobulin Thyroxine in the blood - Total T4, free T4 Transaminases High transaminases Transglutaminase Transferrin - TIBC - TIBC - UIBC - saturation of transferrin Transtyretin Triglyceridemia Triiodothyronine in the blood - Total T3, free T3 Troponin TRH and Troponins of s thymol to TRH TSH - Thyrotropin Uremia Liver values ESR VDRL and TPHA: serological tests for syphlis Volemia Conversion of bilirubin from mg / dL to µmol / L Conversion of cholesterol and triglyceridemia from mg / dL to mmol / L Conversion of creatinine from mg / dL to µmol / L Conversion of blood glucose from mg / dL to mmol / L Conversion of testosteronemia from ng / dL - nmol / L Conversion of uricemia from mg / dL to mmol / L
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