In addition to being naturally present in foods, it is added in fortification to foods and used as a food supplement. The richest nutritional sources of vitamin B2 are: milk and derivatives of all kinds, eggs, offal, green vegetables, meat, mushrooms and oil seeds (especially almonds). In some countries it is common to add cereals and their derivatives with vitamin B2 - not only that, also with thiamine and others of group B.
In the form of a supplement, it is used to prevent and treat specific deficiencies (hypovitaminosis and avitaminosis) and as a remedy for migraines. It can be administered orally or parenterally and its administration is almost always well tolerated; normal doses are considered safe even during pregnancy.
Riboflavin was discovered in 1920, isolated in 1933 and synthesized in 1935. It is included in the World Health Organization (WHO) "Essential Medicines List", which mentions the safest and most effective ones needed by the health system. Riboflavin is available as a generic and over-the-counter drug. Dietary supplementation of vitamin B2 for about 30 days has an approximate cost of 23 euros / 22 US dollars.
clinical non-specific but not negligible, it can specifically compromise various tissues such as the skin, eyes and tongue.in adults, but clinical trials in adolescents and children have produced mixed results.
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