FIBROLAX ® is a drug based on seeds Ispaghula Husk
THERAPEUTIC GROUP: Laxatives - Bulking laxatives
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Indications FIBROLAX ® Psyllium Seeds
FIBROLAX ® is used in the treatment of occasional episodes of constipation.
Mechanism of action FIBROLAX ® Psyllium Seeds
FIBROLAX ® consisting of the integument of Ispaghula seeds (psyllium seeds), is characterized by the exclusive presence of vegetable fibers, in particular mucilage.
Taken orally, it can pass rapidly through the alimentary canal, reaching the intestinal environment unaltered, where - completely inert to the absorption processes - it retains water in the enteric lumen, forming a gelatinous mass useful for increasing the fecal volume.
The fecal mass, supported by the mucilage, can therefore contribute to the stimulation of peristaltic movements, regulating the intensity and frequency of the evacuations.
Studies carried out and clinical efficacy
PSYLLIUM AND METABOLIC SYNDROME
J Clin Gastroenterol. 2010 Sep; 44 Suppl 1: S58-60.
The right fiber for the right disease: an update on the psyllium seed husk and the metabolic syndrome.
Giacosa A, Rondanelli M.
Metabolic syndrome is a rapidly growing disease in the Western population characterized by hyperglycemia / insulin resistance, dyslipidemia, overweight / obesity and hypertension. The addition of psyllium-derived fibers to the common diet of these patients has proved useful not only for its laxative effects, but also in decreasing appetite and improving the lipid profile.
FIBROLAX AND CONSTIPATION
J Int Med Res.
Treatment of chronic constipation by a bulk-forming laxative (Fibrolax).
Borgia M, Sepe N, Brancato V, Costa G, Simone P, Borgia R, Lugli R.
Although FIBROLAX is indicated above all in the treatment of episodic constipation, studies have shown that taking this medicine, even in the case of chronic constipation, can guarantee a reduction in painful abdominal symptoms, with an improvement in the frequency and consistency of bowel movements.
PSYLLIUM: POSSIBLE ANTIDIABETIC ROLE
J Ethnopharmacol. 2005 Nov 14; 102: 202-7. Epub 2005 Sep 8.
Psyllium decreased serum glucose and glycosylated hemoglobin significantly in diabetic outpatients.
Ziai SA, Larijani B, Akhoondzadeh S, Fakhrzadeh H, Dastpak A, Bandarian F, Rezai A, Badi HN, Emami T.
It is known that laxatives, by reducing intestinal transit time, can inhibit the absorption of active and nutrient ingredients. This characteristic has been tested, in reference to psyllium seeds, for the ability to improve the clinical profile of the diabetic patient, proving effective in reducing the levels of glycemia and glycosylated hemoglobin, while improving the concentrations of HDL cholesterol. Despite the encouraging results, the statistics should be expanded in order to obtain more meaningful data.
Method of use and dosage
FIBROLAX ® 3.5 gr Ispaghula Husk sachets or 150 gr jar, with 63.64 gr Ispaghula Husk: the recommended dosage is one sachet or 2 teaspoons, taken after meals, at least 2-3 times a day, for about two or three days.
It is important to take the drug with plenty of water, in order to increase the content of the fecal mass as much as possible. To avoid digestive problems it would be advisable not to go to bed after taking FIBROLAX ® waiting at least one hour.
Any adjustments to the dosage or the period of administration should be decided by the physician, also on the basis of the efficacy of the product and the frequency and consistency of the evacuations.
Warnings FIBROLAX ® Psyllium Seeds
The use of FIBROLAX ® is indicated in the resolution of episodes of occasional constipation, not in the treatment of chronic constipation, where the therapy is based on the evaluation and possible correction of the patient's diet.
In order for the Ispaghula integument to ensure a correct laxative effect, it is necessary to keep the intake of fluids high during the day and while taking the medicine.
The abuse of laxatives can cause the onset of hydro-electrolytic decompensation, with dehydration and hypokalemia (at the basis of side effects affecting the nervous and muscular system) and intestinal atony, characterized by a reduction in peristalsis and chronic constipation.
Although FIBROLAX ® is a drug that can be sold without a prescription, it would always be advisable to consult your doctor or pharmacist before taking it, especially for patients under the age of 12 or suffering from hypertension and endocrine-metabolic disorders.
PREGNANCY AND BREASTFEEDING
As with many laxatives, there are currently no clinical trials useful to understand the safety profile of FIBROLAX ® on the health of the unborn child or newborn, when taken during pregnancy or during the breastfeeding period.
Therefore, it would be preferable to avoid taking FIBROLAX ® during these periods, or to resort to its use only in case of real need and under strict medical supervision.
Interactions
Laxatives, therefore also FIBROLAX ®, are able to accelerate intestinal transit time, reducing the absorption of nutrients and active ingredients. In this regard it would be useful to resort to the use of laxatives only after at least 2 hours from taking other drugs. .
Contraindications FIBROLAX ® Psyllium Seeds
FIBROLAX ® is contraindicated in case of hypersensitivity to the active substance or to one of the excipients.
The use of laxatives is also contraindicated in case of intense abdominal pain, nausea, vomiting, diarrhea, gastro-intestinal affections, even with an acute course, dehydration and in case of intestinal obstruction.
Undesirable Effects - Side Effects
Intestinal distension induced by the mucilage contained in FIBROLAX ® and by the increase in fecal mass, may occasionally be associated with cramping pain, abdominal colic, flatulence and gastrointestinal obstruction. The incidence of these adverse reactions is more frequent in the case of chronic constipation.
The abuse of laxatives can be associated with diarrhea, hypokalemia, dehydration, decreased intestinal motility and chronic constipation.
Note
FIBROLAX ® is an OTC drug, therefore it can be sold freely without the need for a medical prescription.
The information on FIBROLAX ® Psyllium Seeds published on this page may be out of date or incomplete. For a correct use of this information, see the Disclaimer and useful information page.
