As an oral antidiabetic, of course, metformin must be taken by mouth to exercise its activity. There are numerous medicines based on metformin on the market: in some of these it is present as the only active ingredient, while in others it is found in combination with other oral antidiabetic drugs (such as glitazones, sulfonylureas, dipeptidyl-peptidase 4 inhibitors, sodium transporter inhibitors - type 2 glucose). Furthermore, metformin can also be used in combination with insulin.
Medicines based on metformin alone can be sold to the public upon presentation of a repeatable medical prescription (RR), but being classified as group A drugs, they can be dispensed at the expense of the National Health System (SSN). Some of the metformin-based medicines in combination with other antidiabetics, on the other hand, require presentation of a restrictive repeatable medical prescription or RRL (drugs that can be sold to the public only on prescription from hospitals or specialists).
