What is Kre Alkalyn?
Compared to the traditional monohydrate, in which each creatine molecule is complexed with a water molecule, Kre Alkalyn would be easier to absorb; in fact, Kre Alkalyn, unlike monohydrate, enters the digestive tract already "buffered" and therefore does not undergo the negative effect of gastric acid pH which, in aqueous solution, determines the conversion of creatine into the inactive metabolite: creatinine.
Integrate with Kre Alkalyn
Integration with Kre Alkalyn has the purpose of increasing the muscle reserves of CP, naturally present in the body in quantities of about 120g (a value which depends mainly on the muscle mass of the subject, where 95% of the TOT reserves of creatine are stored); the intake dose for Kre Alkalyn, estimated at around 3g / day, should integrate the recommended dietary ration of a sportsman or better of an athlete, naturally included around 2g of creatine per day (achievable above all through meat). For the Kre Alkalyn it is recommended to take it 30 "before training and on an empty stomach, preferably 20" from a pro-insulin meal-supplement (glucose or other forms of carbohydrates with a high glycemic index - GI, possibly accompanied by proteins or from amino acids with a high insulin index].
Obviously, the daily supplementation of Kre Alkalyn (which represents about 2.5% of the total creatine stores in the body) should not be understood as the primary source of creatine intake; in addition to being introduced in the diet, it is efficiently synthesized by the body (kidneys and liver) starting from other amino acids (arginine, glycine, methionine). It is no coincidence that vegetarians seem to have only slightly lower creatine stocks than the rest of the population.
NB. The manufacturer of Kre Alkalyn has carried out numerous studies with long-term administration doses of 10g / day; from the published works no side effects emerge BUT, personally, I believe that these are dosages well outside the recommended safe range. It should be noted that, in the case of a low-calorie diet, the constant intake of Kre Alkalyn could even reach 5g / day to compensate for any food shortage; however, this is purely a consideration personal. Also on an experimental basis, the possible harmful potential for doses of Kre Alkalyn equal to 20g / day for 7 consecutive days was observed; neither symptoms nor particular clinical signs were manifested and this would suggest that it is a safety limit. Personally, I refrain from suggesting or advising against an integrative practice of this magnitude.
ATTENTION! The intake of Kre Alkalyn, as well as that of other forms of creatine, must in no way disregard the logic and recommendations regarding its use; Kre Alkalyn, although it is more protected than monohydrate against conversion / hydrolysis into creatinine (catabolite to be filtered and excreted in the urine), if taken in excessive doses could contribute to causing chronic and potentially exhausting kidney fatigue if evaluated in the long and very long term. We also remember that Kre Alkalyn, as well as monohydrate or other supplements, is not uniformly tolerated; in some subjects (especially with high dosages) it can cause abdominal cramps, nausea, vomiting and diarrhea.
Regarding the above, it can be agreed that integration with Kre Alkalyn is NOT ADVISABLE in case of kidney, liver and heart diseases, as well as in pregnancy, breastfeeding and in young subjects not yet definitively developed.
Why take creatine or Kre Alkalyn?
The intake of Kre Alkalyn can significantly benefit the athletic performance of maximal and submaximal strength and power; the studies reported so far, which however are based on creatine monohydrate (less absorbable), also document an increase in generic anaerobic performance, the reduction of perception of fatigue and the improvement of lung ventilation capacity. Furthermore, the collective experience in Body-Building suggests that, in muscle-building activities, creatine monohydrate (and likely Kre Alkalyn), in subjects who respond positively to supplementation, can contribute to the increase of fat-free mass (FFM) thanks to the osmotic power of the molecule which promotes the increase in fibro-cellular water retention.
While not an impartial assessment, we recall that the producer of Kre Alkalyn (covered by patent) has conducted and published 4 studies focused on the dietary integration of its product; the results were "obviously" positive (otherwise, they would not have been disclosed) and can be summarized as: increase in workload (also with respect to the consumption of creatine monohydrate), increase in protein synthesis in vitro, absence of side effects, lower concentrations of creatinine compared to supplementation with monohydrate, improvement in lipidemia, increase in VO2max compared to supplementation with monohydrate.
Objective and impartial clinical studies on the difference in the integration between creatine monohydrate and Kre Alkalyn
In 2012, an IMPARTIAL (and double-blind) experimental work was published which took into consideration the differences between the creatine monohydrate supplementation and that of Kre Alkalyn in a period of 0-7-28 days (days); the sample analyzed consisted of 36 endurance athletes who were examined: muscle concentrations of creatine, body mass, lean mass, fat mass,% body fat,% of total body water, maximum strength on bench presses and squats ( 1 repetition maximal - RM); WAC mean power, peak power, or total work power; serum blood lipid levels, markers of catabolism and bone status, serum electrolyte status, lymphocyte and Red blood cells.
Muscle creatine content (analyzed with biopsy) and serum content (analyzed with blood sampling) after 7 and 28 days resulted, indiscriminately between monohydrate and Kre Alkalyn, higher than in the previous period. Furthermore, no side effects were highlighted in both cases, an aspect that suggests the inexistence of real chemical and physiological mechanisms for which Kre Alkalyn should be "protective" compared to monohydrate.
In conclusion, the use of creatine monohydrate is comparable - in terms of effectiveness - to that of Kre Alkalyn, which, apart from the significantly higher cost, would not seem to bring additional benefits (even with the same dose of intake).
Bibliography:
- A buffered form of creatine does not promote greater changes in muscle creatine content, body composition, or training adaptations than creatine monohydrate - Jagim AR, Oliver JM, Sanchez A, E Galvan, Fluckey J, Riechman S, M Greenwood, Kelly K, Meininger C, C Rasmussen, Kreider RB. - Department of Health and Kinesiology, Exercise and Sport Nutrition Laboratory, Texas A&M University, College Station, TX 77843-4243, USA. [email protected] - J. Int. Soc. Sports Nutr. 2012 Sep. 13; 9: 43. doi: 10.1186 / 1550-2783-9-43.
