and, in some cases, even the following day. The skin at the administration site becomes painful, swollen and red. In some cases, itching may also arise. This type of reaction, which could also last for a few days, is NOT to be understood as an allergic reaction to the vaccine and is NOT a risk factor for subsequent vaccinations. Some allergic reactions present with mild symptoms, such as hives, but more severe reactions are also possible. The current limited experience with regard to adverse reactions to the COVID-19 vaccine does not allow us to formulate reasonable hypotheses on the causes and mechanisms underlying any allergic reactions.
It is different if we are talking about anaphylaxis, that is a severe allergic reaction, with generally rapid onset (usually occurs within minutes or a few hours of contact with the allergen). The symptoms can be different and related: urticaria, cutaneous angioedema , laryngeal edema, dyspnoea, thoracic constriction, hypotension, up to cardio-circulatory arrest.
How soon does the allergic reaction occur?
Almost half of all allergic reactions to vaccines occur within 15 minutes of dosing. Immediate hypersensitivity reactions are defined, and it is for this reason that the patient who has received the vaccine remains under observation for at least 15 minutes (this time increases to 30 minutes in the case of allergic subjects). Reactions have also been reported 4 hours after vaccination, however it is not possible to exclude the onset of reactions several hours later.
, redness or scarring. In case of skin reactions observe some precautions during exposure to the sun.Post vaccine skin rash remedies
Swelling and / or redness at the injection site can be relieved simply by applying ice locally or a cloth soaked in cold water.
, as a post-Covid-19 vaccine reaction, is a common side effect not only related to coronavirus vaccines. The intensity of this pain varies from subject to subject, and is also variable according to the type of vaccine administered. Some vaccinated people felt more pain, others, on the other hand, do not feel at all. The experts however reassured: pain in the arm, and even any skin rash, are normal responses following the injection of foreign substances into our body: the vaccine. in fact, it simulates the action of a pathogen without causing disease
Several vaccines cause pain around the injection site of the cells APC (from the English Antigen Presenting Cells(antigen-presenting cells) act as a sentinel in our muscles, skin and other tissues. When the presence of the external pathogen is detected, they trigger a chain reaction known as an adaptive immune response.
All three COVID-19 vaccines approved by the FDA they are inoculated by injection into the arm. All of them cause the classic pinch of needle prick. Arm pain that can occur after vaccination, on the other hand, can be of various types: localized and noticeable pain (typical of the Modern and Pfizer post vaccine reaction) or mild and short-lasting ( vaccine J&J). The high intensity of pain in the arm post administration of the vaccines Pfizer And Modern compared to J&J, it resides in the technology used. J&J uses a modified virus to introduce a gene that stimulates our cells to produce the SARS-CoV-2 spike protein, Pfizer And Modern, on the other hand, they act through messenger RNA. RNA, as it is known, is a potent activator of the innate immune system.
There does not seem to be a dangerous relationship between vaccine against Covid-19 and alcohol in moderate quantities.
