peripheral. This condition, defined in medical language with the term neutropenia, can depend on numerous causes, such as, for example, blood diseases, vitamin deficiencies, exposure to toxic agents, use of certain drugs and immune reactions. There are also familial (associated with genetic alterations) and idiopathic (whose cause is unknown) forms.If it becomes particularly severe, the reduction in neutrophils can increase susceptibility to infections.
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genetic-diseases fever eating-behavior-disorders
Usually, low neutrophils do not give rise to symptoms until an infectious state develops; the manifestations that follow can be variable, but fever is always present during the most serious infections.
In the presence of a marked reduction of neutrophils, it is necessary to immediately initiate a broad spectrum empirical antibiotic therapy. Treatment may also include the administration of the granulocyte colony stimulating factor (G-CSF) and the adoption of supportive measures.
found in circulating blood, as they make up 40-75% of leukocytes. Under physiological conditions, these elements play a crucial role in the defense mechanisms of the organism against foreign agents, especially infectious ones, to preserve the biological integrity of the organism.
The alterations of the defective neutrophils can be primitive or acquired.
- Low primitive neutrophils may be due to genetic mutations that result in a defect in neutrophil production, distribution, or functionality;
- Low neutrophils from acquired or secondary causes can be the result of infections, parasites, necrosis and tissue damage, allergic manifestations and the use of certain drugs.
