globular; the determination of their plasma concentration provides useful information on the general state of health and, in particular, supports the diagnosis of various conditions. For example, low beta globulin levels can be a sign of kidney or liver disease. The level of beta globulins can increase, however, in the presence of an inflammatory process and other conditions of increased cell turnover. Alterations of beta globulins can also be found in cases of autoimmune disorders and infectious diseases. Results that deviate from the norm may also be due to certain medications, dehydration or pregnancy.
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. Among the best known proteins of this group are transferrin (responsible for transporting iron) and beta-2 microglobulin.
Other beta globulins that fall into this group are: plasminogen, angiostatins, properdin, sex hormone binding globulin, fibrinogen, complement proteins (in particular, C3 and C4) and lipoproteins (in particular, LDL or low density lipoproteins).
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