ZMA - EUROSUP

Information on ZMA - EUROSUP

ZMA - EUROSUP

Food supplement based on zinc, magnesium and vitamin B6

FORMAT
Pack of 60 capsules

COMPOSITION

Zinc monomethionine
Zinc / Magnesium aspartate
Vitamin B6
Capsule: Gelatin
Stabilizer: microcrystalline cellulose
Anti-caking agents: silicon dioxide

Per capsule: Zinc 7.5 mg - Magnesium 112.5 mg - Vitamin B6 2.62mg

Product features ZMA - EUROSUP

ZMA - it is a zinc and magnesium based product enriched with vitamin B6. Unlike other trace element supplements, this product features a patented formulation, which covalently combines zinc / monomethionine with zinc / magnesium aspartate and vitamin B6. The aforesaid forms represent the best absorbable formulations by the human intestine.

Zinc: essential trace element, as even in trace amounts it participates in the safeguarding of correct cellular functionality by participating in numerous reactions such as:

Cofactor of different enzymatic classes;
Structural factor that guarantees the functionality of transcription factors, antioxidant enzymes and structural membrane proteins;
Regulator of gene transcription, cell cycle, intracellular signaling and hormonal function.

It is found in good quantities in products of animal origin, but also in some vegetables such as legumes and cereals. However, the one present in meat, eggs and fish is more bioavailable, as it is complexed with methionine which improves its absorption in the intestine. In plants, on the other hand, the absorption of zinc is inhibited by the presence of phytic acid. The LARNs set a recommended daily dose of 10 mg for men and 7 mg for women, which is easily achieved and surpassed by a healthy diet. Nowadays zinc deficiencies are very rare and generally some risk categories can be identified, including children and adolescents, pregnant women, patients undergoing parenteral nutrition, patients suffering from pathologies of the gastro-intestinal tract and vegans.
Magnesium: trace element present for about 25 grams in the human body and concentrated mainly in the skeleton (60%) and muscle (27%). It is part of various cellular reactions (more than 300), three of which:

Energy production: magnesium is a cofactor of numerous enzymes involved in glucose metabolism and in the synthesis of ATP;
Anabolic reactions: participates in the synthesis of the most important macromolecules of our organism;
Structural role: it is part of the formation of cell membranes and bone tissue;
Cell function regulation: involved in both cell-singalling and cell migration.

The recommended daily dose is around 350 mg / 400 mg, which can be satisfied with a simple diet, considering that it is found in good quantities in whole grains, almonds and peanuts, in some vegetables, bananas and in quantity modest in meat. Its deficiencies, however rare, are associated with gastrointestinal pathologies, kidney disorders, drug therapies with diuretics, alcoholism and old age. Magnesium deficiencies are accompanied by a decrease in calcium, with a consequent increase in PTH (parathyroid hormone), which in the long run leads to bone thinning, loss of appetite, nausea, vomiting and behavioral changes.
Vitamin B6: group of water-soluble vitamins which includes pyridoxal, pyridoxine and pyridosamine. The coenzymatic form expressed in humans is a phosphorylated ester known as pyridoxalphosphate, which is obtained following the absorption of vitamin B6 at the duodenal level, plasma transport, hepatic modification and storage at the tissue level. Vitamin B6 is involved in numerous reactions, including which we can mention:

Glucose metabolism: gluconeogenesis and glycogenolysis;
Neurotransmitter synthesis: it is part of the synthesis of serotonin;
Maintenance of erythrocyte functionality: it is included as a coenzyme in the synthesis of the EME group;
Control of hormonal activity;
Synthesis of nucleic acids.

The LARN suggest the daily intake of 1.1 mg of vitamin B6 for women and 1.5 mg for men, which can be easily satisfied with a balanced diet containing products of animal origin.

Rationale for use - ZMA - EUROSUP

This product was born as an endogenous stimulator of anabolic metabolism, but there are many doubts about its effectiveness. In fact, there is talk of a study conducted by prof. It shines in Washington, where supplementation with 30 mg of zinc monomethionine / aspartate, 450 mg of magnesium / aspartate and 10.5 mg of Vitamin B6 for 8 weeks, before bedtime, would have increased total and free testosterone levels by more than 30%, of IGF-1 (important messenger with anabolic function) by 3.6% and improved athletic performance. However, the aforementioned study, not only is not published in the largest database in the world, but has been promptly denied by two subsequent studies, in which no increase in testosterone and IGF1 levels was recorded, nor any improvement in athletic performance or composition. corporeal.
The scientific literature, on the other hand, seems to agree on the effect of trace elements, and especially of magnesium, in supporting and improving athletic performance both from a metabolic and hormonal point of view.

Method of use recommended by the company - ZMA - EUROSUP

Swallow one serving (1 capsule) per day, 30-60 minutes before bedtime, with water or other liquid of your choice

Method of use in sports practice - ZMA - EUROSUP

There are currently no studies showing an effective dosage for this supplement.
If you want to replicate the doses used in the only study showing positive effects on testosterone levels, you should take 4 capsules a day, preferably on an empty stomach.
In this case, however, diarrheal episodes or abdominal pain cannot be completely excluded.
Zinc: the most effective dose seems to be 3 mg / kg;
Magnesium: the most studied and effective dose seems to be that of 10 mg / kg;

ZMA side effects - EUROSUP

Zinc: high amounts of zinc introduced are responsible for abdominal pain, diarrhea, nausea and vomiting. Chronic zinc administration (60 mg / day total) is associated with copper deficiency.
Magnesium: high amounts of magnesium are responsible for profuse diarrhea. The increase in serum magnesium levels is instead associated with hypotension, confusion, heart rhythm disturbances, deterioration of renal function, fatigue, breathing difficulties, even cardiac arrest.The safe supplementation dose appears to be 350mg / day.
Vitamin B6: chronic administration can be responsible for damage to the nervous system and neuropathies of various levels already at doses above 200mg / day.

ZMA - EUROSUP interactions

Zinc: in addition to interfering with other trace elements such as copper, it could reduce the absorption of some antibiotics such as tetracyclines, reducing their effectiveness.
Magnesium: may interfere with some antibiotics, tranquilizers and oral anticoagulants, reducing their effectiveness.

Precautions for use ZMA - EUROSUP

The product is contraindicated in cases of renal or hepatic pathology, cardiovascular disease and / or hypertension, during pregnancy, during lactation and under 14 years.

This article, elaborated on the critical rereading of scientific articles, university texts and common practice, is for information purposes only and therefore has no medical prescription value. It is therefore always required to consult your doctor, nutritionist or pharmacist before undertaking the use of any supplement.. Learn more about ZMA's critical analysis - EUROSUP.

BIBLIOGRAPHY

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Effects of Zinc Magnesium Aspartate (ZMA) Supplementation on Training Adaptations and Markers of Anabolism and Catabolism.
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J Int Soc Sports Nutr. 2004 Dec 31; 1: 12-20

Effect of fatiguing bicycle exercise on thyroid hormone and testosterone levels in sedentary males supplemented with oral zinc.
Kilic M.
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Eur J Appl Physiol. 2010 Jan; 108: 363-9. Epub 2009 Oct 9.
Magnesium sulfate enhances exercise performance and manipulates dynamic changes in peripheral glucose utilization.
Cheng SM, Yang LL, Chen SH, Hsu MH, Chen IJ, Cheng FC.
Eur J Appl Physiol. 2010 Jan; 108: 363-9. Epub 2009 Oct 9.
The effect of magnesium supplementation on lactate levels of sportsmen and sedanter.
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Acta Physiol Hung. 2006 Jun; 93 (2-3): 137-44.