Information about Kre-alkalyn Maximize
KRE-ALKALYN - MAXIMIZE
Food supplement based on Kre-Alkalyn creatine monohydrate
FORMAT
Pack of 120 capsules
COMPOSITION
Kre-Alkalyn creatine monohydrate
Capsule: food gelatin, maltodextrin
Anti-caking agent: magnesium stearate
Per capsule: Creatine monohydrate Kre-Alkalyn 750 mg
For maximum daily dose (4 capsules): Creatine monohydrate Kre-Alkalyn 3000 mg
Product features Kre-alkalyn Maximize
Alkaline creatine is a patented product. Synthesized in the laboratory, it was created with the aim of improving stability in an aqueous environment and its intestinal absorption.
Creatine monohydrate commonly found on the market is characterized by a pH of around 6.9, which in aqueous environment involves a "high conversion into creatinine, an inactive metabolite. In the" alkaline "formulation the pH rises up to 12, delaying, and according to the house producer by canceling, the
extra muscle conversion into creatinine. All this should translate into a greater availability of the biologically active product, a reduction of potential side effects, an improvement in pharmacokinetic properties and finally an enhancement of the benefits. However, it is difficult to express a critical opinion given the absence of noteworthy clinical trials, and the presence of only studies carried out and / or financed by the same manufacturer.
Creatine - present for about 120 grams in the body of a 70kg man, it is concentrated for 95% in the muscles, and for the remainder between brain and heart. The requirement for an adult and healthy individual is about 2 grams per day , equal to the average amount excreted in the urine in the form of creatinine, half that can be recovered through endogenous synthesis and half through food intake. The endogenous synthesis begins in the kidney starting from arginine and glycine, then ends in the liver through the addition of methionine by the enizma SAM. The quota introduced through the feeding with foods of animal origin (mainly meat), reaches the intestinal level, where it is partly absorbed by the enterocytes through a mediated sodium cotransport. Through the circulatory stream, together with the endogenous one, creatine will thus reach muscle tissue, where it compensates for the amount lost during muscle contraction. At the skeletal muscle level, creatine will be able to carry out its biological role, initially being phosphorylated by the creatine kinase enzyme, and then yielding its phosphoric group to the ADP, guaranteeing the synthesis of ATP. The ATP thus produced will support muscle contraction during the first minute of intense exercise, and then leave room for other metabolic pathways of energy production. Part of the muscle phosphocreatine pull will undergo a process of non-enzymatic hydrolysis, which will mediate its transformation into creatinine and its subsequent disposal in the kidney.
Rationale for integrating Kre-alkalyn Maximize into sports practice
The benefits obtainable from supplementation with creatine monohydrate are well documented and characterized by an "intense study activity, which in the last 20 years has made creatine one of the most successful supplements in sports practice.
Among the effects accepted almost unanimously by the scientific world it is possible to remember:
- The improvement of maximal and submaximal strength and power;
- The improvement of anaerobic performance;
- The reduction of the sensation of muscle fatigue;
- The improvement of ventilatory skills;
To these are added, albeit still under debate, the "myprotective action and the improvement of body composition."
Unfortunately, the same cannot be said for alkaline creatine, given the absence of standardized clinical trials published in reliable scientific journals. However, the manufacturer of this alternative form of creatine publishes 4 different studies on its website from which it emerges:
- 25.85% increase in workload compared to athletes supplemented with conventional creatine monohydrate at the same dose;
- Increased in vitro protein synthesis compared to creatine monohydrate;
- Absence of side effects;
- Reduction in creatinine levels compared to creatine monohydrate;
- Improvement of the lipid profile;
- Significant improvement in VO2max, compared to the group supplemented with creatine monohydrate.
Method of use recommended by the company - Kre-alkalyn Maximize
It is recommended to take 2-4 capsules a day, preferably 30 minutes before training in case of sports activity.
Directions for use in sports Kre-alkalyn Maximize
Contrary to what can be described for creatine monohydrate, for which there are different supplementary protocols tested, the absence of publications does not allow us to understand how much the supplementation with alkaline creatine differs from that of monohydrate.
Surely, it would be advisable to maintain the quotas suggested by the manufacturer, even if in the previously described works different dosages emerge, ranging from 3 grams / day up to 10 grams / day.
The capsule form should also prevent any contact with acidic liquids (for example fruit juice, used to solubilize creatine), potentially harmful transformation into creatinine, and preserve its content in the best possible way.
According to the same principle, therefore, the intake should be recommended on an empty stomach in order to avoid an increase in acidity due to digestion.
Kre-alkalyn Maximize synergies
Carbohydrates + Creatine: taken in the hour before the race, they guarantee an important energy support. Furthermore, the muscle uptake of creatine seems significantly enhanced by the insulin released following the intake of carbohydrates, with an increase of over 60% compared to the one obtainable with creatine alone.
Furthermore, some evidence shows an increase in the levels of the glucose transporter GLUT 4, on the muscle tissue following the intake of creatine, with an increase in the glycogen resynthesis capacity; this action could be used in the post-workout anabolic window.
Carbohydrates + creatine + proteins: guarantees an increase in absorption comparable to that present for simple carbohydrates only. In this case, however, there would be a potential advantage both on the nutritional intake of the snack and a reduction in the potentially dangerous glycemic peak.
CLA + creatine + proteins: at doses of 6 g, 9 g and 36 g respectively taken for 5 weeks, it has been shown to be effective in improving strength and increasing muscle mass by 3 - 4% in combination with strength training.
Arginine + Creatine: appears to provide a better ergogenic boost with an increase in maximum peak strength.
Kre-alkalyn Maximize side effects
Various studies agree that creatine supplementation in healthy individuals is safe. In particular, studies relating to chronic (3-5 gr / day for a year) and acute (20 gr / day for a week) supplementation do not show any effects. particular collateral.
However, it should be remembered that the ingestion of too high or poorly solubilized doses could be accompanied by abdominal cramps, nausea, vomiting and diarrhea, as well as chronic administration, especially if carried out in conjunction with high-protein diets could significantly increase the renal load.
Finally, even if it does not represent a real side effect, it must be considered that the increase in weight resulting from the accumulation of water inside the cell could have a negative impact on performance.
Precautions for use Kre-alkalyn Maximize
The product is contraindicated in cases of renal or hepatic pathology, cardiovascular disease and / or hypertension, during pregnancy, during lactation and under the age of 12 and adolescents not yet formed.
In case of prolonged use (over 6/8 weeks) the doctor's opinion is necessary.
This article, elaborated on the critical rereading of scientific articles, university texts and common practice, is for information purposes only and therefore has no medical prescription value. It is therefore always required to consult your doctor, nutritionist or pharmacist before undertaking the use of any supplement.. Learn more about Kre-alkalyn Maximize's critical analysis.