Absorption rate of a drug

CHEMICAL PROPERTIES AND IMPORTANT PHYSIOLOGICAL VARIABLES THAT AFFECT DRUG ABSORPTION

Chemical Properties

chemical nature

molecular weight

solubility

partition coefficient

gastric mobility

presence of food in the stomach

pH at the absorption site

absorbent surface area

blood flow

presystemic elimination

SPEED OF ABSORPTION

The rate of absorption varies depending on the route of administration used

The plasma concentration of a drug per unit of time depends on the difference between the amount absorbed and the amount eliminated.

The peak plasma concentration of a drug depends on the rate of absorption: the slower the absorption, the lower the plasma peak.

Other articles on "Rate of absorption of a drug"

1. Absorption of a drug
2. Absorption of a drug - Henderson-Hasselbach equation -