CHEMICAL PROPERTIES AND IMPORTANT PHYSIOLOGICAL VARIABLES THAT AFFECT DRUG ABSORPTION
Chemical Properties
chemical nature
molecular weight
solubility
partition coefficient
gastric mobility
presence of food in the stomach
pH at the absorption site
absorbent surface area
blood flow
presystemic elimination
SPEED OF ABSORPTION
The rate of absorption varies depending on the route of administration used
The plasma concentration of a drug per unit of time depends on the difference between the amount absorbed and the amount eliminated.
The peak plasma concentration of a drug depends on the rate of absorption: the slower the absorption, the lower the plasma peak.
Other articles on "Rate of absorption of a drug"
- Absorption of a drug
- Absorption of a drug - Henderson-Hasselbach equation -
