endowed with anticoagulant activity belonging to the group of New Oral Anticoagulants (NAO). More precisely, it is a direct inhibitor of the coagulation factor Xa.
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Editorial board Edoxaban - Chemical Structure
Naturally, as NAO, in order to carry out its therapeutic action, this active principle must be administered orally. Currently (April 2019), the only medicinal product available in Italy based on edoxaban is Lixiana®, in which the active ingredient is found in the form of edoxaban tosilate. It is a prescription medicine only upon presentation of a repeatable limitative medical prescription (RRL - medicine that can be sold to the public only on prescription from hospitals or specialists.) However, since it is a product classified as a Class A drug, its cost can be reimbursed by the National Health System (SSN).