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The stiffness of the muscles begins to cause discomfort, especially if it invades the neck area. Movements become slower and slower and this condition obviously hinders the performance of normal daily activities, such as washing, putting on shoes or writing. The facial expression also changes, becoming more rigid, and not devoid of expression, and gradually there may be a significant increase in the amount of saliva in the mouth, as the muscles responsible for swallowing lose their original efficiency.
«First Part - Motor Symptoms of Parkinson's Disease
it often brings with it mood disorders. Among these, the most common manifestation is depression which can precede motor symptoms or occurs within a year of the onset of the disease. Other times, however, all the typical symptoms of depression, from apathy to lack of interest in rewarding activities or distress, appear when the disease is already in an advanced stage.
Anxiety crises as well as a permanently apathetic attitude can represent alarm bells or appear long after diagnosis.
To try to explain the reason for the recurrence of depression in people with Parkinson's disease, two theories have been hypothesized:
- In the first, depression is considered as "reactive", due to progressive functional disability;
- In the second, depression is considered as an integral part of the pathology, understood as a primary alteration of the amines present in the brain.