There are different forms of Burkitt's lymphoma:
- Endemic form (equatorial Africa) which often presents as a cheek tumor with an increase in the volume of the facial bones and jaw;
- Sporadic form (non-African) which tends to affect the abdomen;
- Forms related to immunodeficiency.
In the endemic form, Burkitt's lymphoma appears to be closely related to the infection caused by the Epistein-Barr virus; however, the actual role of this infection in the etiology of lymphoma is not yet fully understood.
As for the variant related to immunodeficiency, however, it is often associated with HIV infection (in fact, Burkitt's lymphoma can sometimes be a pathology indicative of the presence of AIDS), or it can affect those patients who take immunosuppressive drugs. following a transplant.
and in the testicles, medulla, brain and belly, causing pain.The disease can cause apathy, swelling, sore throat, general malaise, swelling of the jaw bones, heavy sweating, mucosal ulcers.
it exerts a discreet resolving effect in a good part of the cases. More precisely, to cure this neoplastic form, combined chemotherapy at high doses (with several antineoplastic drugs - polychemotherapy) constitutes the treatment of choice, while mono-chemotherapy does not seem particularly suitable.
Given the speed with which Hodgkin's lymphoma develops, it is essential to start treatment quickly.
Among the therapeutic schemes that can be implemented, we recall the CODOX-M / IVAC regimen - which involves the administration of multiple anticancer chemotherapy drugs, such as: cyclophosphamide, vincristine, doxorubicin, high dose methotrexate / ifosfamide, etoposide, high cytarabine doses - combined with rituximab (a monoclonal antibody). This therapeutic scheme appears to be curative in over 80% of children and adults under the age of 60 affected by Burkitt's lymphoma.
For patients over 60, on the other hand, the association between rituximab and polychemotherapy based on etoposide, prednisone, vincristine and doxorubicin seems to be more successful.
PLEASE NOTE
The information on Burkitt's lymphoma medications above is for illustrative purposes only and is not intended to replace the direct relationship between a healthcare professional and patient.
It is up to the physician to choose the most suitable treatment scheme for the patient, based on the type and severity of the disease, the patient's state of health and his or her response to treatment.
Always consult your doctor and / or specialist before taking any drug or product in case of Burkitt's lymphoma.
